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Vitamins Offer Hope for Alzheimer’s


Article Source: Health And Fitness Journal

By Dr. Mercola

In the United States, Alzheimer’s disease is currently at epidemic proportions, with 5.4 million Americans—including one in eight people aged 65 and over—living with the disease, according to the Alzheimer’s Association’s 2011 Alzheimer’s Disease Facts and Figures1.

By 2050, this is expected to jump to 16 million, and in the next 20 years, it is projected that Alzheimer’s will affect one in four Americans, rivaling the current prevalence of obesity and diabetes.

There is still no known cure for this devastating disease, and very few treatments. Alzheimer’s drugs are often of little to no benefit at all, which underscores the importance of prevention throughout your lifetime.

Research repeatedly suggests the best hope for patients lies in prevention through optimal diet, exercise and staying socially and mentally active. As recently reported by Forbes2:

“[A] new study in Science suggested that last year’s ‘breakthrough’ pharmaceutical, bexarotene (Targretin) – a cancer drug that had initially received wide publicity for helping break up the plaques in Alzheimer’s – doesn’t seem to do this very well at all, and can have significant adverse side effects for the patient.

‘Something happened in that initial report – either something technically or otherwise, which we can’t put our hands on at this point in time,” study author Sangram Sisodia told US News & World Report. ‘Something is seriously wrong.’

While memory loss is common among Westerners, it is NOT a “normal” part of aging. Research has shown that even mild “senior moments” are caused by the same brain lesions associated with Alzheimer’s disease and other forms of dementia. These cognitive changes are by no means inevitable!

People who experience very little decline in their cognitive function up until their deaths have been found (post-mortem) to be free of brain lesions, showing that it’s entirely possible to prevent the damage from occurring in the first place. At the end of this article, I share my best tips for maintaining healthy brain function well into old age.

In recent years, researchers studying natural compounds have offered new hope. For example, two recent studies suggest that compounds in cinnamon, as well as vitamins B12, B6, and folate may delay the onset and/or slow progression of the disease.

The Promise of Cinnamon and Vitamins in the Fight Against Alzheimer’s Disease

The first study in question, published in the Journal of Alzheimer’s Disease3, found that cinnamaldehyde and epicatechin, two compounds found in cinnamon, have an inhibitory effect on the aggregation of a particular protein called tau. Tau plays a large role in the structure and function of neurons.

But while a normal part of cell structures, this protein can begin to accumulate, forming “neurofibrillary tangles” that are a hallmark of Alzheimer’s disease. Both compounds were found to protect tau from oxidative damage that can lead to dysfunction.

Donald Graves, adjunct professor in UCSB’s Department of Molecular, Cellular, and Developmental Biology and co-author of the study explained the protective process to Medical News Today4:

“‘Take, for example, sunburn, a form of oxidative damage. If you wore a hat, you could protect your face and head from the oxidation. In a sense this cinnamaldehyde is like a cap. While it can protect the tau protein by binding to its vulnerable cysteine residues, it can also come off,’ Graves added, which can ensure the proper functioning of the protein.”

It’s interesting to note that there’s a high correlation between type 2 diabetes and Alzheimer’s disease. Some even believe Alzheimer’s may be a form of brain diabetes. Insulin and insulin receptors in your brain are crucial for learning and memory, and it’s known that these components are lower in people with Alzheimer’s disease.

In addition to the above findings, cinnamon has also been found to have beneficial effects on blood glucose management in type 2 diabetics. This is one of the reasons I include cinnamon in my healthy coconut candy recipe.

B Vitamins Again Show Promise in Alzheimer’s Prevention

The other study, published in Proceedings of the National Academy of Sciences5, found that vitamins B6, B12, and folic acid may help slow the progression of the disease, confirming and supporting previous studies. As reported in the featured article6:

“The fact that B-family vitamins may play a significant role in dementia, or more specifically in warding it off has been consistently illustrated. What is news from the current study, however, is that high-dose B-vitamin treatment in people at risk for the disease ‘slowed shrinkage of whole brain volume,’ and especially reduced shrinkage in areas known to be affected in Alzheimer’s disease.”

The 156 study participants, all of whom were over the age of 70, were diagnosed with mild cognitive impairment. This, along with midlife hypertension, midlife obesity and diabetes, is a known risk factor for Alzheimer’s. One group of participants received a placebo while the other received high-dose B-vitamin treatment consisting of:

  • 0.8 mg folic acid
  • 20 mg vitamin B6
  • 0.5 mg vitamin B12

It is important to note that vitamin B12 comes in many forms and it is typically injected because it is not absorbed well by most people, especially in the elderly who need it most. This is due to it being one of the largest vitamins known. The most common form is cyanocobalamin but a better from would be methylcobalamin. A better alternative to B12 injections would also be sublingual sprays, which are absorbed very similarly to the injections.

The treatment effectively slowed shrinkage of the whole brain volume over the course of two years. It also reduced, by as much as seven-fold, the cerebral atrophy in certain brain regions that are particularly vulnerable to damage associated with Alzheimer’s disease. Another major boon: The supplements cost less than 50 cents a day and are readily available in pharmacies and health-food stores. In the placebo group, higher homocysteine levels at baseline were associated with faster atrophy in these same regions. According to the researchers7:

“We… show that the beneficial effect of B vitamins is confined to participants with high homocysteine… and that, in these participants, a causal Bayesian network analysis indicates the following chain of events: B vitamins lower homocysteine, which directly leads to a decrease in gray matter atrophy, thereby slowing cognitive decline.

Our results show that B-vitamin supplementation can slow the atrophy of specific brain regions that are a key component of the AD process and that are associated with cognitive decline.”

Dr. A. David Smith, professor emeritus of pharmacology at Oxford University, founding director of the Oxford Project to Investigate Memory and Ageing, and senior author of the study told Bloomberg News8 that this B-vitamin treatment is “the first and only disease-modifying treatment that’s worked. We have proved the concept that you can modify the disease.” This shouldn’t come as a surprise to anyone who understands that without proper nutrition and exercise, your brain will be increasingly vulnerable to damage with age…

Vitamin B Cocktail Already Used for Dementia Prevention in Sweden

Three years ago, the same group of researchers showed that the atrophy rate in patients’ whole brains was reduced by about 30 percent in those taking the vitamin cocktail9. The atrophy rate was even higher—53 percent—in those who had elevated homocysteine levels, a benefit that was reconfirmed in the featured study. According to Bloomberg10:

“The studies, known as Vitacog, were funded by seven charities and government agencies and vitamin maker Meda AB of Solna, Sweden. Smith is an inventor on three patents held by Oxford University for B vitamin formulations to treat Alzheimer’s disease… Vitamin B12 is found in liver, fish and milk and folic acid in fruit and vegetables. Deficiency of folate and B vitamins is already linked to dementia…

Doctors in Sweden began measuring homocysteine in people who report declining memory about two years ago, said [Johan] Lokk [professor and head physician in the geriatric department at Karolinska University Hospital in Sweden, who wasn’t involved in the study]...

Swedish patients with high homocysteine are given folic acid and B vitamins, even if they aren’t deficient. ‘We think the increased homocysteine level could be deleterious to the brain,’ Lokk said. ‘We wanted to be on the offensive in diagnosing and treating patients. In our opinion, it is harmless and cheap.’”

General Anesthesia Could Increase Risk of Dementia in Elderly by 35 Percent

Related research suggests that being exposed to general anesthesia can increase the risk of dementia in the elderly by as much as 35 percent. The research was presented at the annual congress of the European Society of Anesthesiology (ESA). As reported by Medical News Today11:

“Postoperative cognitive dysfunction, or POCD, could be associated with dementia several years later. POCD is a common complication in elderly patients after major surgery. It has been proposed that there is an association between POCD and the development of dementia due to a common pathological mechanism through the amyloid β peptide. Several experimental studies suggest that some anesthetics could promote inflammation of neural tissues leading to POCD and/or Alzheimer’s disease (AD) precursors including β-amyloid plaques and neurofibrillary tangles.”

Participants aged 65 and over were followed for a total of 10 years. Participants exposed to at least one general anesthetic over the follow-up had a 35 percent increased risk of developing a dementia compared to those who were not exposed to anesthesia. According to lead researcher Dr. Francois Sztark12:

“These results are in favor of an increased risk for dementia several years after general anesthesia. Recognition of POCD is essential in the perioperative management of elderly patients. A long-term follow-up of these patients should be planned.”

Tips for Avoiding Alzheimer’s Disease

The beauty of following my revised Nutrition Plan is that it helps treat and prevent all chronic degenerative diseases, from the common ones like heart disease, diabetes, obesity and Alzheimer’s to the ones you have never heard of or can’t even pronounce. So please read the Plan as soon as you can. It is divided into three helpful sections, Beginner, Intermediate and Advanced to help you start at the right level.

The plan is the first step in addressing Alzheimer’s disease, which is currently at epidemic proportions, with 5.4 million Americans – including one in eight people aged 65 and over – living with the disease.

Remember, while memory loss is indeed common among Westerners, it is NOT a “normal” part of aging, and cognitive changes are by no means inevitable. People who experience very little decline in their cognitive function up until their deaths have been found (post-mortem) to be free of brain lesions, showing that it’s entirely possible to prevent the damage from occurring in the first place… and one of the best ways to do this is by leading a healthy lifestyle.

  • Sugar and Fructose. Ideally, you’ll want to keep your sugar levels to a minimum and your total fructose below 25 grams per day, or as low as 15 grams per day if you have insulin resistance or any related disorders.
  • Improve magnesium levels. There is some exciting preliminary research strongly suggesting a decrease in Alzheimer symptoms with increased levels of magnesium in the brain. Unfortunately, most magnesium supplements do not pass the blood brain levels, but a new one, magnesium threonate, appears to and holds some promise for the future for treating this condition and may be superior to other forms.
  • Optimize your vitamin D levels with safe sun exposure. Strong links between low levels of vitamin D in Alzheimer’s patients and poor outcomes on cognitive tests have been revealed. Researchers believe that optimal vitamin D levels may enhance the amount of important chemicals in your brain and protect brain cells by increasing the effectiveness of the glial cells in nursing damaged neurons back to health.

    Vitamin D may also exert some of its beneficial effects on Alzheimer’s through its anti-inflammatory and immune-boosting properties. Sufficient vitamin D is imperative for proper functioning of your immune system to combat inflammation that is also associated with Alzheimer’s.

  • Keep your fasting insulin levels below 3. This is indirectly related to fructose, as it will clearly lead to insulin resistance. However other sugars (sucrose is 50 percent fructose by weight), grains and lack of exercise are also important factors. Lowering insulin will also help lower leptin levels which is another factor for Alzheimer’s.
  • Vitamin B12: In addition to the research presented above, a small Finnish study published in the journal Neurology13 also found that people who consume foods rich in B12 may reduce their risk of Alzheimer’s in their later years. For each unit increase in the marker of vitamin B12, the risk of developing Alzheimer’s was reduced by two percent. Remember sublingual methylcobalamin may be your best bet here.
  • Eat a nutritious diet, rich in folate, such as the one described in my nutrition plan. Vegetables, without question, are your best form of folate, and we should all eat plenty of fresh raw veggies every day. Avoid supplements with folic acid, which is the inferior synthetic version of folate.
  • High-quality animal-based omega-3 fats, such as krill oil. (I recommend avoiding most fish because, although fish is naturally high in omega-3, most fish are now severely contaminated with mercury.) High intake of the omega-3 fats EPA and DHA help by preventing cell damage caused by Alzheimer’s disease, thereby slowing down its progression, and lowering your risk of developing the disorder.
  • Avoid and eliminate mercury from your body. Dental amalgam fillings, which are 50 percent mercury by weight, are one of the major sources of heavy metal toxicity. However you should be healthy prior to having them removed. Once you have adjusted to following the diet described in my optimized nutrition plan, you can follow the mercury detox protocol and then find a biological dentist to have your amalgams removed.
  • Avoid aluminum, such as antiperspirants, non-stick cookware, vaccine adjuvants, etc.
  • Exercise regularly. It’s been suggested that exercise can trigger a change in the way the amyloid precursor protein is metabolized14, thus, slowing down the onset and progression of Alzheimer’s. Exercise also increases levels of the protein PGC-1alpha. Research has also shown that people with Alzheimer’s have less PGC-1alpha in their brains11 and cells that contain more of the protein produce less of the toxic amyloid protein associated with Alzheimer’s. I would strongly recommend reviewing the Peak Fitness Technique for my specific recommendations.
  • Avoid flu vaccinations as most contain both mercury and aluminum, well-known neurotoxic and immunotoxic agents.
  • Eat blueberries. Wild blueberries, which have high anthocyanin and antioxidant content, are known to guard against Alzheimer’s and other neurological diseases. Like any fruit though, avoid excesses here.
  • Challenge your mind daily. Mental stimulation, especially learning something new, such as learning to play an instrument or a new language, is associated with a decreased risk of Alzheimer’s. Researchers suspect that mental challenge helps to build up your brain, making it less susceptible to the lesions associated with Alzheimer’s disease.
  • Avoid anticholinergic and statin drugs. Drugs that block acetylcholine, a nervous system neurotransmitter, have been shown to increase your risk of dementia. These drugs include certain nighttime pain relievers, antihistamines, sleep aids, certain antidepressants, medications to control incontinence, and certain narcotic pain relievers.

Statin drugs are particularly problematic because they suppress the synthesis of cholesterol, deplete your brain of coenzyme Q10 and neurotransmitter precursors, and prevent adequate delivery of essential fatty acids and fat-soluble antioxidants to your brain by inhibiting the production of the indispensable carrier biomolecule known as low-density lipoprotein.

Other Natural Treatments for Your Anti-Alzheimer’s Arsenal

Finally, there are a few other nutritional recommendations worth noting for their specific benefits in preventing and treating dementia. So, although your fundamental strategy for preventing dementia should involve a comprehensive lifestyle approach, you may want to consider adding a few of these natural dietary agents to your anti-Alzheimer’s arsenal. These four natural foods/supplements have good science behind them, in terms of preventing age-related cognitive changes:

  1. Coconut Oil: The primary fuel your brain needs for energy is glucose. However, your brain is able to run on more than a single type of fuel, one being ketones (ketone bodies), or ketoacids. Ketones are what your body produces when it converts fat (as opposed to glucose) into energy.

    The medium-chain triglycerides (MCT) found in coconut oil are GREAT source of ketone bodies, because coconut oil is about 66 percent MCTs. In fact, ketones appear to be the preferred source of brain food in patients affected by diabetes or Alzheimer’s.

  2. Astaxanthin is a natural pigment with unique properties and many clinical benefits, including some of the most potent antioxidant activity currently known. As a fat-soluble nutrient, astaxanthin readily crosses your blood-brain barrier. One study15 found it may help prevent neurodegeneration associated with oxidative stress, as well as make a potent natural “brain food.”

    The molecules of astaxanthin neutralize free radicals and other oxidants without being destroyed or becoming pro-oxidants themselves in the process. It’s is a unique molecule whose shape allows it to precisely fit into a cell membrane and span its entire width. In this position, astaxanthin can intercept potentially damaging molecules before they can damage your cells.

    You can get some astaxanthin by taking krill oil, which is a fantastic omega-3 fat supplement. But you can boost your astaxanthin even MORE by adding a pure astaxanthin supplement to your nutritional regimen. For optimal absorption, make sure to take krill oil and/or astaxanthin with a fat-containing meal, since both are fat-soluble.

  3. Gingko biloba: Many scientific studies have found that Gingko biloba has positive effects for dementia. Gingko, which is derived from a tree native to Asia, has long been used medicinally in China and other countries. A 1997 study from JAMA showed clear evidence that Gingko improves cognitive performance and social functioning for those suffering from dementia.

    Research since then has been equally promising. One study in 2006 found Gingko as effective as the dementia drug Aricept (donepezil) for treating mild to moderate Alzheimer’s type dementia. A 2010 meta-analysis found Gingko biloba to be effective for a variety of types of dementia.

  4. Alpha lipoic acid (ALA): ALA can stabilize cognitive functions among Alzheimer’s patients and may slow the progression of the disease.


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Biotechnology and Biological Sciences Research Council Has Links to GMOs


Article Source: Health And Fitness Journal

By Dr. Mercola

The Biotechnology and Biological Sciences Research Council (BBSRC) is one of seven UK Research Councils, which are funded by the government’s Department for Business, Innovation and Skills.

Their vision, as stated on their Web site, is “to lead world-class 21st century bioscience, promoting innovation and realizing benefits for society within and beyond the UK.”1

The UK government is known to be very receiving to genetically modified organisms (GMO) and last year the UK’s Agriculture Biotechnology Council (ABC) even published a new report “Going for Growth,” which, according to GMWatch, “calls for GM to be put at the heart of agricultural development in the UK.”2

While ABC is not a government authority — it’s a GM industry lobby group that represents the interests of Monsanto, Bayer, DuPont, Syngenta and other biotech giants – the organization met with key UK government officials to present their case, and reportedly “the industry’s push for GM is already being welcomed.”

This indeed appears to be the case, as now evidenced by a significant connection between BBSRC and a leading biotech research firm, Rothamsted Research.

BBSRC Is Rothamsted’s Largest Funder, Tied to Fraudulent Research

The Biotechnology and Biological Sciences Research Council is the largest funder of Rothamsted Research. This publically funded firm is working on developing projects like genetically modified wheat that deters aphids and genetically modifying wheat and other seeds to change the contents of minerals, fatty acids and other nutrients.

Last year a group of 400 protestors, including farmers, politicians and activists, demonstrated outside an open-air test plot for Rothamsted’s GM wheat, voicing concerns that it could contaminate other crops and take away consumers’ access to non-GM wheat.

Professor Maurice Moloney, head of Rothamsted Research, also authored a statement from the UK’s Science Media Centre (which is funded by Monsanto, Syngenta and other biotech giants) that attempted to debunk an independent study demonstrating harm from eating genetically engineered food…

Yet Rothamsted Research is in no place to be discrediting other research. In fact, they have a joint laboratory with China under the direction of Guangyuan He, a researcher whose 2012 study on GM wheat was recently retracted due to fraudulent content “with serious consequences to wheat production and its economic impact.”3

This is the same group of researchers who also retracted a separate study on GM wheat last year after claiming they were having trouble replicating the findings.4

Ironically, all the links to Rothamsted’s Web pages mentioning its Joint Lab with China and its ties to Guangyuan He were mysteriously no longer working at the time of this writing.5

Government Ties to the Biotech Industry Are Not Confined to the UK…

It’s not only the UK government that appears to be selling out its citizens, funding GM research and allowing GM crops to be planted even as mounting evidence points to their significant environmental and human health risks.

In the US, Monsanto?a company that admits it wants to own the world’s food supply through its patented genetically engineered seeds?spends millions lobbying Congress each year. Monsanto’s legislative agenda also includes the U.S. Department of Agriculture (USDA), the Food and Drug Administration (FDA), and the Environmental Protection Agency (EPA) — all of which have a say in whether or not you get to know whether the food you’re eating has been genetically engineered.

To get an idea of just how broad and deep Monsanto’s reach is, take a look at the following chart. Over the years, this biotech giant has successfully infiltrated an ever-increasing number of high-level federal regulatory positions in the US government, many of which are positions meant to protect your food safety. The bottom line is that the biotech industry is becoming intertwined with vast sections of government’s around the globe, successfully blurring the line between the agencies meant to protect the food supply and those who wish to control it…

Why Is Caution Warranted for GMOs?

Many consumers around the globe are still in the dark about the very real risks that GM crops pose. The Canadian news station CBC News recently reported that despite warnings that GM foods could destroy the environment and pose risks to agricultural diversity, most Canadians have “no strong views on the matter.” Andreas Boecker, an associate professor at the University of Guelph who has researched consumer acceptance of GM foods, told CBC News:6

“These concerns among farmers and informed groups of consumers do not translate to the average consumer. They are too far removed from the concerns of the farming community… And if you go by shopping behavior most foods that they buy have some share of GMOs.”

This is precisely what the biotech industry wants, even as increasing research demonstrates GM crop dangers. One recent study found that rats fed a type of genetically engineered corn that is prevalent in the US food supply for two years developed massive mammary tumors, kidney and liver damage, and other serious health problems. This was at dietary amounts of about 10 percent. If you live in the US and you eat processed foods, your diet probably contains far more than 10 percent GM foods…

Last year, University of Canterbury Professor Jack Heinemann also released results from genetic research he conducted on a type of GM wheat, which showed with ‘no doubt’ that molecules created in the wheat, which are intended to silence wheat genes to change its carbohydrate content, may match human genes and potentially silence them. This could lead to significant changes in the way glucose and carbohydrates are stored in the human body, which could be potentially deadly for children and lead to serious illness in adults.

A 2012 nutritional analysis of GMO corn versus non-GMO corn also showed that these two foods are not essentially equal, as both the biotech industry and government agencies like to claim. Instead, shocking differences in nutritional content were found showing non-GMO corn contains 437 times more calcium, 56 times more magnesium, and 7 times more manganese than GMO corn.7

It’s important to realize that genetically engineered foods have never been proven safe for human consumption over a lifetime, let alone over generations. The longest industry-funded animal feeding study was 90 days, which recent research has confirmed is FAR too short. In the world’s first independently funded lifetime feeding study, massive health problems set in during and after the 13th month, including organ damage and cancer. Not to mention, there is no safety monitoring. Once the GE item in question has been approved, not a single country on earth is actively monitoring and tracking reports of potential health effects, which means we may never know their true consequences, that is, until it’s too late.

Did You Know the Purported “Benefits” of GM Crops Are Largely Untrue?

The authors of the report GMO Myths and Truths8 (who include Michael Antoniou, PhD, a 28-year veteran of genetic engineering technology who has himself invented a number of gene expression biotechnologies, as well as John Fagan, PhD, a leading authority on food sustainability, biosafety, and GMO testing) took a science-based approach to evaluating the available research, and came to the conclusion that most of the scientific evidence regarding safety and increase yield potential do not support the claims made at all.

In fact, the evidence demonstrates that the claims for genetically engineered foods are not just wildly overblown; they simply aren’t true. It makes it all the more alarming that the UK and US governments continue to give GM crops a green light when these authors concluded GM crops:

Are laboratory-made, using technology that is totally different from natural breeding methods, and pose different risks from non-GE crops Can be toxic, allergenic and less nutritious than their natural counterparts Are not adequately regulated to ensure safety
Do not increase yield potential Do not reduce pesticide use but increase it Create serious problems for farmers, including herbicide-tolerant “superweeds,” compromised soil quality, and increased disease susceptibility in crops
Have mixed economic effects Harm soil quality, disrupt ecosystems, and reduce biodiversity Do not offer effective solutions to climate change
Are as energy-hungry as any other chemically-farmed crops Cannot solve the problem of world hunger but distract from its real causes – poverty, lack of access to food and, increasingly, lack of access to land to grow it on  

 

According to their report, there are three major potential sources of adverse health effects from genetically engineered foods:

  1. The genetically modified gene product – for example, the Bt toxin in GM insecticidal crops may be toxic or allergenic
  2. The GM transformation process may produce mutagenic effects, gene regulatory effects, or effects at other levels of biological structure and function that result in new toxins or allergens and/or disturbed nutritional value
  3. Changes in farming practices linked to the use of a genetically modified organism may result in toxic residues – for example, higher levels of crop contamination with the herbicide Roundup are an inevitable result of using GM Roundup Ready® crops

In the UK GM Foods Must Be Labeled, But NOT in the US

Even as their government continues to fund and welcome GMOs, residents of the UK at least have the ability to identify foods that contain GMOs by their labels. In fact, this is the case in the entire European Union (EU). According to the Food Standards Agency:9

In the EU, if a food contains or consists of genetically modified organisms (GMOs), or contains ingredients produced from GMOs, this must be indicated on the label. For GM products sold ‘loose’, information must be displayed immediately next to the food to indicate that it is GM.”

This is in stark contrast to the US, where GM foods are still not labeled. But chances are, if you eat processed foods, your diet is chock full of GM ingredients you didn’t even know about — causing equally unknown consequences to your health. GM crops already in production in the US include:10

Alfalfa (first planting 2011) Canola (approx. 90% of US crop) Corn (approx. 88% of US crop in 2011)
Cotton (approx. 90% of US crop in 2011) Papaya (most of Hawaiian crop; approximately 988 acres) Soy (approx. 94% of US crop in 2011)
Sugar Beets (approx. 95% of US crop in 2010) Zucchini and Yellow Summer Squash (approx. 25,000 acres) Animal products (milk, meat, eggs, honey, etc.) because of contamination in feed

 

Common ingredients derived from these ubiquitous GM crops, which are added to the majority of US processed foods, include:11

Amino Acids Aspartame Ascorbic Acid Sodium Ascorbate
Vitamin C Citric Acid Sodium Citrate Ethanol
Flavorings (“natural” and “artificial”) High-Fructose Corn Syrup Hydrolyzed Vegetable Protein Lactic Acid
Maltodextrins Molasses Monosodium Glutamate Sucrose
Textured Vegetable Protein (TVP) Xanthan Gum Vitamins Yeast Products


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Yet Another Reason Why Dr. Oz Cannot Be Trusted: False Claims About Red Palm Oil


Article Source: Health And Fitness Journal

Dr. Oz is a powerful guy, blessed with a name that conjures up wizardry. He just unveils his latest “miracle,” which seems to happen on an almost daily basis, and people scamper off to the nearest the health food. Recently the great Oz anointed the oil extracted from the fruit of the palm tree that grows in Indonesia and Malaysia as a wonder product that can aid weight loss and reduce the risk of Alzheimer’s and heart disease. Introduced to this marvel by his a guest, a homeopath, Dr. Oz excitedly gushed about the beta carotene and “special form of vitamin E” found in “red palm oil.” A curious business. Tell me, does a Professor of Surgery at Columbia University with over 400 research publications under his belt really need advice on nutrition from a homeopath?

As is usually the case with Oz’s miracles, there is a seed of truth that then gets fertilized with lots of verbal manure until it grows into a tree that bears fruit dripping with unsubstantiated hype. For example, one study did show a reduction in the severity of cholesterol-induced atherosclerosis in rabbits fed high doses of red palm oil. This has little relevance for humans but magicians who pull rabbits out of hats may consider adding red palm oil to the diet of their little assistant. The red colour of the oil comes from beta-carotene, the same substance that contributes to the hue of carrots and many other fruits and vegetables. It is the body’s precursor for vitamin A, which makes it an important nutrient.

Unfortunately, in many areas of the developing world there is a shortage of both beta carotene and vitamin A in the diet leading to a high incidence of blindness, skin problems and even death. In such cases red palm oil would be useful, but of course there are numerous other ways to introduce beta-carotene into the diet including “golden rice” that has been genetically modified to provide the nutrient. Aside from remedying a vitamin A deficiency, there is not much evidence for increased intake of beta carotene outside of that contained in a balanced diet. There are suggestions that higher blood levels of beta carotene reduce the risk of breast cancer in high-risk women, but the beta-carotene levels may just be a marker for a better diet.

As far as the Alzheimer’s connection goes, Oz may have been referring to a study in which 74 seniors with mild dementia were compared with 158 healthy seniors. People with dementia had lower levels of beta-carotene and vitamin C in their blood. Again, this does not prove that the lower levels are responsible for the condition, they may just signal a diet that is poorer in fruits and vegetables. Tocotrienols, the “special form of vitamin E” Oz talked about, have shown some borderline effects in Alzheimer’s patients at doses way higher than found in red palm oil. There is no evidence for preventing the disease.

What about the claim that red palm oil causes loss of belly fat? That seems to come from a rat study in which a tocotrienol-rich fraction extracted from palm oil caused a reduction in fat deposits in the omentum, the tissue that surrounds organs. There was no evidence of abdominal fat reduction, and furthermore, the study involved putting the animals on an unnatural and unhealthy diet. But these are not the facts that the audience was treated to on the Dr. Oz Show.

What the eager viewers witnessed were three visually captivating but totally irrelevant demonstrations of the purported health benefits of red palm oil. First in line was a piece of apple that had turned brown because of “oxidation.” This could be prevented with a squirt of lemon juice, Oz explained. Then came the claim that red palm oil protects our brain the same way that lemon juice protects the apple. This is absurd. Vitamin C inactivates polyphenol oxidase, the enzyme that allows oxygen to react with polyphenols in the apple resulting in the browning. The human brain, however, bears no resemblance to an apple, except perhaps for the brains of those who think it does. Yes, oxidation is a process that goes on in the human body all the time and has been linked with aging but suggesting that beta-carotene because of its antioxidant effects protects the brain like lemon juice protects the apple is inane.

Just as zany was the next demo in which two pieces of plastic half-pipe representing arteries were shown with clumps of some white guck, supposedly deposits that lead to heart disease. Oz poured a gooey liquid, representing “bad fats” down one of the tubes, highlighting that it stuck to the goo. Then he proceeded to pour red palm oil down the other pipe and lo and behold, the deposits washed away. Totally meaningless and physiological nonsense. The homeopath then explained that saturated fats behave like thick molasses cruising through the cardiovascular system, but palm oil does not, despite being high in saturated fats. While saturated fats may lead to deposits, they do not do this by “thickening” the blood. Arterial deposits are the result of some very complex biochemistry and are not caused by “sludge” in the blood. Oz even exclaimed that this demo was indicative of how red palm oil reduces cholesterol in a month by 40%, better than drugs. A search of Pubmed reveals no such study.

The final demonstration involved Dr. Oz lighting a candle and a flare, without wearing safety glasses mind you. The message seemed to be that the body burns most fats slowly, but it burns red palm oil with great efficiency, preventing weight gain. Where does this come from? Possibly some confusion about medium chain triglycerides which are somewhat faster metabolized than other fats. But these are not found in palm oil. They are found in coconut oil and palm kernel oil. Oz and his homeopath expert were as confused about this as about the rest of red palm oil info they belched out.

Aside from scientists who took issue with the misleading information, animal rights groups also attacked Oz’ exhortations about the benefits of the oil claiming that it will lead to destroying larger stretches of the jungle, home to many wild creatures including the orangutan. They maintain that when the jungle is cleared every living creature is either captured or killed and adult orangutans are often shot on sight. A tragedy. Another tragedy is that Dr. Oz could be doing so much good if he just focused on real science, as he sometimes does, instead of drooling over the latest “miracle” as presented by some pseudo expert.

***

Joe Schwarcz, Ph.D., is the Director of McGill University’s Office for Science and Society and teaches a variety of courses in McGill’s Chemistry Department and in the Faculty of Medicine with emphasis on health issues, including aspects of “Alternative Medicine”.  He is well known for his informative and entertaining public lectures on topics ranging from the chemistry of love to the science of aging.  Using stage magic to make scientific points is one of his specialties.

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