Researchers have found that the most striking differences between autistic and normal brains were loss of the purkinje cell layer in the cerebellum, and also activation of the microglia, which are cells that are central to the inflammatory response.
The inflammatory response is your body’s defense against invasion, but in autism, it seems to be turned against itself. It seems there is an inflammatory war going on in the brains of autistic children and adults.
According to Psychology Today:
“Other studies have shown that autism is possibly an autoimmune disease of some kind … the immune system is not only fighting external invaders or bad guys in the body, such as viruses, bacteria, or newly-formed cancer cells, but also has started to attack presumably healthy tissues of the body.
In the evolutionary medicine paradigm, autoimmune disorders are diseases of civilization, caused by our highly inflammatory diets and stressful lifestyles.”