The omega-3 fat docosahexanoic acid, or DHA, reduced the size of tumors in mice and made a chemotherapy drug more potent while limiting its harmful effects.
The findings add to evidence showing a range of health benefits from eating omega-3 fats.
Researchers looked at how DHA affected solid tumors growing in mice, and how well it interacted with the chemotherapy drug cisplatin. At the molecular level, DHA reduces the accumulation of white blood cells, systemic inflammation, and a harmful condition marked by decreased antioxidant levels — all of which have been linked to tumor growth.
Their experiment also showed that the fatty acid reduced toxicity and injury to kidney tissue caused by the chemotherapy drug.